- McGill University, B.Sc. Biochemistry, 1998
- Boston University, Ph.D., Biochemistry, 2004
Danielle is a Patent Agent and assists in the preparation of U.S. patent applications and U.S. national phase applications. Her technical expertise includes biochemistry, physiology, molecular biology, pharmaceuticals, medical devices, cell culture engineering, recombinant protein expression, gene expression, fluorescent microscopy, energy metabolism and animal model experimentation, across a wide variety of therapeutic areas.
Prior to joining Volpe and Koenig, Danielle worked as a medical writer where she prepared congress abstracts, research manuscripts, review articles and presentations on a variety of therapeutics and medical devices under clinical development. In addition to this, she was involved with publication planning, drafting scientific statements, gap analyses and literature analyses for pharmaceutical industry clients.
Danielle also has extensive experience as a research scientist. Her doctoral work focused on vesicle trafficking and transport of glucose into cells, as well as the regulation of catecholamine-induced lipolysis. Following graduate school, Danielle did a post-doctoral fellowship at the University of Pennsylvania, where she studied the effects of cytokine signaling on pancreatic beta-cells using transgenic mouse models. As a scientist, she co-authored numerous scientific publications and grants and presented her work at major scientific meetings.
Choi, SM, Tucker DF, Gross DN, Easton RM, Monks BR, Birnbaum MJ. Insulin regulates lipolysis via a compartmentalized Akt-independent signaling pathway. Molecular and Cellular Biology 2010, Nov; 30(21): 5009-20.
Gross DN, Wan M, Birnbaum MJ. The role of FOXO in the regulation of metabolism. Current Diabetes Reports 2009, Jun; 9(3): 208-14.
Gross DN, Van den Heuvel AJP, Birnbaum MJ. The role of FoxO in the regulation of metabolism. Oncogene 2008, Apr 7; 27(16): 2320-36.
Gleason CE, Gross DN, Birnbaum MJ. When the usual insulin is just not enough. Proceedings of the National Academy of Sciences USA 2007, May 22; 104(21): 8681-2.
Gross DN, Miyoshi H, Hosaka T, Zhang HH, Pino EC, Souza S, Obin M, Greenberg AS, Pilch PF. Dynamics of lipid droplet associated proteins during hormonally-stimulated lipolysis in engineered adipocytes: Stabilization and lipid droplet binding of ADRP/Adipophilin. Molecular Endocrinology 2006, Feb; 20(2): 459-66.
Hosaka T, Brooks CC, Presman E, Kim SK, Zhang Z, Breen M, Gross DN, Sztul E, Pilch PF. p115 Interacts with the Glut4 vesicle protein, IRAP, and plays a critical role in insulin-stimulated Glut4 translocation. Molecular Biology of the Cell 2005, Jun; 16(6): 2882-90.
Gross DN, Farmer SR, Pilch PF. Glut4 Storage Vesicles Without Glut4: Transcriptional regulation of insulin-dependent vesicular traffic. Molecular and Cellular Biology 2004, Aug; 24(16): 7151-7162.
Csordas G, Santra M, Reed CC, Eichstetter I, McQuillan DJ, Gross D, Nugent MA, Hajnoczky G, Iozzo RV. Sustained down-regulation of epidermal growth factor receptor by decorin. A mechanism for controlling tumor growth in vivo. Journal of Biological Chemistry 2000, Oct. 20; 275(42): 32879-87.
Life Beyond the Law
I am a Pilates and Yoga enthusiast and love to hike, bike and kayak whenever I get the chance. I enjoy the symphony, cooking, traveling and playing the piano. But my favorite times are spent with my husband and two young kids.